Gene: [12^/GSTMS1] glutathione S-transferase, microsomal, 1;
FUN | [1]
Glutathione S-transferase participates in metabolism of various endogenous
and exogenous hydrophobic substances. It has a wide substrate specificity.
[2] Systematic name: RX:glutathione R-transferase. [3] The catalyzed reaction: RX + glutathione = HX + R-S-G." |
MOP | In contrast to soluble glutathione transferases, the product of GSTMS1 gene functions better as a trimer." |
EVO | Microsomal glutathione transferase gene differs drastically from other known GST genes in both nucleotide and amino acid sequences." |
FAG | [1] Another gene
encoding microsomal glutathione transferase is mapped to Chr 4: GEM:04q/GSTMS2. See also GEM:00.0/GSTMS3. [2] On GST gene family and glutathione transferase classification, see FAM:GST/00.0." |
REF | PRO,MOP,LOC,FAG,POL "DeJong JL &: Genomics, 6, N2, 379-382,
1990 PRO,MOP,LOC,FAG,POL "DeJong JL &: CCG, 51, (HGM10), 986, 1989 PRO,COD,MOP "DeJong JL &: JBC, 263, 8430-8436, 1988 CLO,SEQ,GEN "Kelner MJ &: Genomics, 36, 100-103, 1996 FUN,MEB "McLellan &: Biochem J, 258, N1, 87-93, 1989 |
SWI | SWISSPROT: P10620 |
KEY | xen, mem |
CLA | coding, basic |
LOC | 12 |
MIM | MIM: 138330 |
EZN | ENZYME: 2.5.1.18 |
